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Stimuli-like ionizing radiation, chemotherapeutics, and other drug damage, oxidative stress, and senescence-induced telomere dysfunction can mediate such damage, subsequently leading to the aggregation of aberrant macromolecular substances

More studies are needed to explore the mechanism of natural products side effect

In tumor cells, the apoptosis pathway is often impeded by various mechanisms, many of which contribute to intrinsic resistance to chemotherapy, the most prevalent anticancer therapy (104)

This selectivity has positioned GHK as a candidate research tool for studying copper trafficking and copper-dependent cellular processes, separately from its direct signaling effects

Charlotte Haus GHK-Cu (Copper Tripeptide-1) is a peptide composed of glycine, histidine, and lysine, bound to a copper ion