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Finally, the fermentation was scaled up in a 5-L fermentor, and the highest titer and yield were improved to 5680 mg/L and 45.13 mg/g, respectively, by optimizing the addition conditions of amino acids (40 mM added after 40 h)

Glutathione is a water-soluble antioxidant that plays an important role in Phase II detoxification processes in the liver.

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