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Candida overgrowth affects people of all ages and backgrounds, but certain groups carry significantly higher risk: women (particularly those who use oral contraceptives or have experienced multiple pregnancies), individuals who have completed one or more courses of broad-spectrum antibiotics, people with diabetes or insulin resistance (elevated blood glucose directly feeds yeast proliferation), those taking corticosteroids or other immunosuppressive medications, and individuals under chronic psychological stress

and the stabilization of the extracellular matrix, hemostasis, and the activation of growth factors [50,56]

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and a third portion was fixed in 10% formalin for at least 48 h for histopathological examination