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Baier et al
After 48 h, the mice were sacrificed, and the tumors as well as major organs (heart, liver, spleen, lung, kidney) were collected to measure their fluorescence intensity
The starting compound shown in the picture to the left is an unstable intermediate that is generated from chorismate by the chorismate mutase
Dzyadevych, S
CHE showed strong cytotoxic activity against human melanoma cell lines (A375, G-361, and SK-MEL-3) with IC 50 values below 0.55 g/ml compared with anticancer drugs (etoposide, cisplatin, and hydroxyurea), indicating that CHE has high anticancer potential in melanoma (Tuzimski et al., 2021)
