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10.1152/physrev.00035.2007 [DOI] [PubMed] [Google Scholar] 23.Liu Q, Graeff R, Kriksunov IA, Jiang H, Zhang B, Oppenheimer N, et al

Many patients begin to notice improvements in energy and body composition within a few weeks of starting therapy

Hydroxocobalamin is preferred because it binds more tightly to serum proteins, creating a depot effect that allows slower release and longer duration of action

Ideal candidates typically include: Body composition goals: Individuals focused on reducing body fat percentage while preserving lean muscle mass, those who have reached plateaus with diet and exercise alone, patients seeking metabolically selective approaches without growth hormones broader effects, or individuals interested in targeted fat reduction (particularly abdominal/visceral fat)

Your Nexa provider will confirm what is appropriate for your goals and health history