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Adverse renal response to decongestion in the obese phenotype of heart failure with preserved ejection fraction

A meta-analysis of randomized controlled trials comparing GLP-1 RAs and SGLT2is in patients with obesity and T2D uncontrolled on metformin found that GLP-1 RA use was associated with significantly reduced HbA1c ( 0.40%

Some of the most common side effects are: Nausea Constipation Headache Vomiting Dizziness Insomnia Dry mouth Diarrhea Additional side effects include: Anxiety Hot Flush Fatigue Tremor Upper abdomen pain Viral gastroenteritis Influenza (Flu) Tinnitus (Ringing in the ears) Urinary tract infection Excessive sweating Irritability Increased blood pressure Changes in taste and smell Rashes Muscle strains Palpitations
