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[DOI] [PMC free article] [PubMed] [Google Scholar] 245.Burmeister M.A., Ayala J.E., Smouse H., Landivar-Rocha A., Brown J.D., Drucker D.J., Stoffers D.A., Sandoval D.A., Seeley R.J., Ayala J.E

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Interestingly, dipeptidyl peptidase-4 (DPP4) inhibitors enhance the endogenous GLP-1 levels and enhance GABAergic transmission in rat hippocampal neurons in vivo [232]

After 6 months, those taking the semaglutide had average blood sugar reductions of 0.6% to 1.1%, with bodyweight reduction of around 5 pounds for the 14-mg dose