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Smaller, more frequent meals may be better tolerated than large portions, especially during the initial titration phase when side effects are most common

FIGURE 9: PATENT TYPES FOR TIRZEPATIDE FIGURE 10: ANNUAL PATENT FILINGS FOR TIRZEPATIDE FIGURE 11: DURATION OF PATENT PROTECTION FOR TIRZEPATIDE PERPETUATING HEALTH INEQUITIES The rise of GLP-1 products containing semaglutide and tirzepatide have had an immediate impact on the treatment of diabetes and obesity

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The most successful treatments currently available include glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs), exemplified by semaglutide (approved in 2017, $19.9 billion sales in 2023) 3 and tirzepatide (approved in 2022, $5.3 billion sales in 2023) 4

Magnetic resonance spectroscopy