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3- Alpha-synuclein, LRRK2 and GBA are emerging as some of the most important biologic targets in the pipeline

N Engl J Med 375:18341844 Thompson AM, Trujillo JM (2015) Dulaglutide: the newest GLP-1 receptor agonist for the management of type 2 diabetes

Trial participants on tirzepatide averaged 20.2% reduction versus 13.7% with semaglutide over 72 weeks

The frustration of a weight loss plateau can make the idea of combining treatments feel like a necessary next step

This helps maintain hormonal balance, reducing the risk of excessive hormone levels and making it a safer, more natural option for many patients