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Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity - Frontiers in Endocrinology Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity - JAMA Internal Medicine Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes - New England Journal of Medicine Tirzepatide for Diabetes Improves Glycemic Control After Switch From GLP-1RA - Endocrinology Advisor Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension - Diabetes, Obesity and Metabolism

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Orforglipron (ATTAIN-1) Overall AE rate: 83.4%86.6% Discontinuation due to AEs: 5.3%10.3% (vs