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The Daily Protocol: Take it once daily, first thing in the morning on an empty stomach
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What Is the Duration of Action of Retatrutide

Long-Term Semaglutide Use: Duration and Sustainability Emerging evidence suggests that some patients maintain benefits from extended semaglutide therapy spanning years

Researchers believe this effect is related to how GLP-1 receptor agonists modulate the brains reward pathways, particularly dopamine signaling in the mesolimbic system
