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Treatment with exenatide, a GLP-1 receptor agonist, was comparable to placebo in slowing the rate of Parkinsons disease progression over 96 weeks of treatment, according to a phase 3 study published in The Lancet

doi: 10.3389/fcell.2022.960999 Received 03 June 2022 Accepted 15 August 2022 Published 02 September 2022 Volume 10 - 2022 Edited by Rosa E Navarro, National Autonomous University of Mexico, Mexico Reviewed by Maria Fernanda Hornos Carneiro, Pontificia Universidad Catlica de Chile, Chile Christian Eckmann, Faculty of Natural Sciences I, Martin Luther University of Halle-Wittenberg, Germany Updates Copyright 2022 Vanden Broek, Han and Hansen

These medications work through several mechanisms, including slowing gastric emptying (though this effect may attenuate over time), acting on appetite centers in the hypothalamus, and enhancing feelings of fullness

[DOI] [PubMed] [Google Scholar] 150.Marsk R, Jonas E, Rasmussen F, Nslund E

Without this, we cannot succeed in reducing overdose deaths at a meaningful scale