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Protein needs should be individualized, with general targets of 1.2-1.6 g/kg body weight for many adults, though lower amounts may be appropriate for those with chronic kidney disease or other conditions requiring protein modification

The clinical trial safety data applies exclusively to weekly dosing

Results A total of 11 studies were included in this meta-analysis, including 6 studies on GLP-1 RA, 1 study on GLP-1 and GIP dual receptor agonists, 1 study on orlistat, 2 studies on phentermine-topiramate, and 1 study on naltrexone-bupropion (Additional file 1: Table S2) [22,23,24,25,26,27,28,29,30,31,32]

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