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Comparative efficacy, safety, and cardiovascular outcomes with once-weekly subcutaneous semaglutide in the treatment of type 2 diabetes: Insights from the SUSTAIN 17 trials

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INTRODUCTION In 1983, GLP-1 was found in the quest for the discovery of a glucagon gene [3]

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Impaired glucose tolerance and insulin resistance are associated with increased adipose 11beta-hydroxysteroid dehydrogenase type 1 expression and elevated hepatic 5alpha-reductase activity

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Headache was reported as an adverse event during treatment with liraglutide, semaglutide, phentermine/topiramate, and naltrexone/bupropion, though it was not a severe adverse event

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Available: [16] C

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